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METTLER TOLEDO
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Image Search Results
Journal: Naunyn-Schmiedeberg's Archives of Pharmacology
Article Title: Liraglutide modulates cyclooxygenase and α7 acetylcholine receptors: in vitro and in silico insights into its anti-inflammatory role in LPS-induced inflammation in RAW 264.7 macrophages
doi: 10.1007/s00210-025-04225-5
Figure Lengend Snippet: Effects of Liraglutide on LPS-induced PG elevations in the presence and absence of non-selective nAChR or α7nAChR antagonists. Shown are the effects of liraglutide (10 nM) on 1 µg/ml LPS -induced Prostaglandin E2 ( A ), 6-keto prostaglandin F1α ( B ), Thromboxane A2 ( C ) levels with or without mecamylamine (MEC, 50 μΜ) or methyllycaconitine (MLA, 1 μΜ). Data are shown as mean ± S.E.M. (*, p < 0.05 vs control; †, p < 0.05 vs LPS group; ‡, p < 0.05, vs LPS + VAR, n = 6). LPS: Lipopolysaccharide, MEC: mecamylamine, MLA: methyllycaconitine
Article Snippet: Initially, crystal structures of
Techniques: Control
Journal: Naunyn-Schmiedeberg's Archives of Pharmacology
Article Title: Liraglutide modulates cyclooxygenase and α7 acetylcholine receptors: in vitro and in silico insights into its anti-inflammatory role in LPS-induced inflammation in RAW 264.7 macrophages
doi: 10.1007/s00210-025-04225-5
Figure Lengend Snippet: Predicted interactions of liraglutide (PDB: 4 APD) with ( A ) α7nAChR (PDB: 7EKP), B COX-2 (PDB: 3LN1), and C Prostacyclin Synthase (PDB: 3B6H) modeled with HADDOCK 2.4. protein–protein docking server
Article Snippet: Initially, crystal structures of
Techniques:
Journal: Naunyn-Schmiedeberg's Archives of Pharmacology
Article Title: Liraglutide modulates cyclooxygenase and α7 acetylcholine receptors: in vitro and in silico insights into its anti-inflammatory role in LPS-induced inflammation in RAW 264.7 macrophages
doi: 10.1007/s00210-025-04225-5
Figure Lengend Snippet: Predicted interactions of GLP-1 (PDB: 3IOL) with ( A ) Alpha 7 Nicotinic Acetylcholine Receptor (PDB: 7EKP), B COX-2 (PDB: 3LN1), and C Prostacyclin Synthase (PDB: 3B6H) modeled with HADDOCK 2.4. protein–protein docking server
Article Snippet: Initially, crystal structures of
Techniques: